This amplifies the many challenges associated with GLP-1s, like gastrointestinal side effects, nutrient inadequacies, muscle and bone loss, low long-term adherence, weight regain, and high costs
Martins FL, Bailey MA, Girardi ACC
[DOI] [PubMed] [Google Scholar] 1177.Saunders J.A., Rogers L.C., Klomsiri C., Poole L.B., Daniel L.W
When we consume a wide variety of whole-food plants, lean proteins, and healthy fats, we support GLP-1 activity, optimize gut health, and can more easily maintain a healthy weight, Dr
Figure 1: A metabolic use-case comprehensive patient journey view with taXonomy Pathways In clinical trials, GLP-1 drugs showed high adherence (over 85% of patients stayed on therapy), yet real-world use tells a different story: one large study found only 32% of obese patients remained on a GLP-1 therapy after one year, with just 27% meeting standard adherence thresholds
doi: 10.1111/jdi.14346 51 Petkovi-DabiJBiniICariBBoiLUmievi-ipkaSBednarukNet al